Last update
4/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.2
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
Supplement Facts
Serving Size: 2 Veg Capsule
Amount Per Serving
%DV
Beta-1,3/1,6-D-Glucan Powder (from Saccharomyces cerevisiae)
500 mg
*
ImmunEnhancer [Arabinogalactan from Larch Tree (Larix occidentalis)]
400 mg
*
Top Medical Research Studies
9
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
8
S. cerevisiae aids autoimmune treatment
We evaluated the effects of Saccharomyces cerevisiae and its selenized form, Selemax, on experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
Read More
7
We explored the effects of a yeast (Saccharomyces cerevisiae)-exclusion diet alongside surgery on patients with hidradenitis suppurativa over six years. Our study involved 185 patients, with 37 receiving treatment at our center. Remarkably, 70% of those on the diet noticed improvements in their symptoms.
Additionally, we found that 87% experienced recurrence of skin lesions shortly after consuming yeast. Our findings hint at a link between hidradenitis suppurativa and food intolerance, which may provide insight into its management, particularly regarding inflammation reduction.
Additionally, we found that 87% experienced recurrence of skin lesions shortly after consuming yeast. Our findings hint at a link between hidradenitis suppurativa and food intolerance, which may provide insight into its management, particularly regarding inflammation reduction.
Read More
Most Useful Reviews
7.5
Boosted immunity effectively.
5 people found this helpful
I ordered beta-glucans on my doctor’s recommendation to enhance my immune system. After starting the supplement, I noticed increased energy and improvements in my health. I am pleased with the product quality and feel confident in its benefits.
Read More
7.5
Improved immunity
1 people found this helpful
I ordered it to enhance my daughter's immunity, and perhaps due to its effectiveness, she has not experienced the usual atopy this year. I am considering continuing to give it to her. The packaging is very thorough.
Read More
6
Best quality product.
1 people found this helpful
I have ordered this supplement several times due to its quality. There is indeed a noticeable effect from it.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.2
- All Researches
9
We explored a novel oral drug delivery system designed specifically for treating IgA nephropathy, an autoimmune disorder. Using hydroxychloroquine and dexamethasone paired with yeast cell walls, we aimed for targeted delivery to the ileal region.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Read More
9
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
9
We investigated the effects of a novel treatment targeting BAMBI, a protein involved in immune cell regulation, on autoimmune disorders like psoriasis and arthritis in mice. Through careful experimentation with control groups, we found that the anti-BAMBI antibody significantly increased protective Treg cells and reduced disease progression in various models. This treatment effectively prevented skin psoriasis and type II collagen-induced arthritis, hinting at new therapeutic possibilities for chronic inflammatory conditions driven by immune system dysfunction.
Read More
8
S. cerevisiae aids autoimmune treatment
We evaluated the effects of Saccharomyces cerevisiae and its selenized form, Selemax, on experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
Read More
7
Saccharomyces cerevisiae shows immune modulation
We explored how ABBi16, a blend of β-glucans from Saccharomyces cerevisiae, impacts immune responses in the context of autoimmune conditions. Our findings indicate that ABBi16 effectively promotes Th1 responses while increasing IL-10 and IL-22 secretion, contributing to a balanced immune response. Notably, this compound did not trigger IL-17 production, which is an inflammatory marker, suggesting that it is a safe oral supplement for those with autoimmune disorders. Overall, ABBi16 shows promise in promoting a more regulated immune system.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Boosted immunity effectively.
5 people found this helpful
I ordered beta-glucans on my doctor’s recommendation to enhance my immune system. After starting the supplement, I noticed increased energy and improvements in my health. I am pleased with the product quality and feel confident in its benefits.
Read More
7.5
Improved immunity
1 people found this helpful
I ordered it to enhance my daughter's immunity, and perhaps due to its effectiveness, she has not experienced the usual atopy this year. I am considering continuing to give it to her. The packaging is very thorough.
Read More
6
Best quality product.
1 people found this helpful
I have ordered this supplement several times due to its quality. There is indeed a noticeable effect from it.
Read More
4
Less effective product
I ordered this because I believed beta-glucan might be effective, but it does not seem to compare favourably to the previous product I consumed.
Read More
Frequently Asked Questions
7.5
Boosted immunity effectively.
5 people found this helpful
I ordered beta-glucans on my doctor’s recommendation to enhance my immune system. After starting the supplement, I noticed increased energy and improvements in my health. I am pleased with the product quality and feel confident in its benefits.
7.5
Improved immunity
1 people found this helpful
I ordered it to enhance my daughter's immunity, and perhaps due to its effectiveness, she has not experienced the usual atopy this year. I am considering continuing to give it to her. The packaging is very thorough.
7
Saccharomyces cerevisiae shows immune modulation
We explored how ABBi16, a blend of β-glucans from Saccharomyces cerevisiae, impacts immune responses in the context of autoimmune conditions. Our findings indicate that ABBi16 effectively promotes Th1 responses while increasing IL-10 and IL-22 secretion, contributing to a balanced immune response. Notably, this compound did not trigger IL-17 production, which is an inflammatory marker, suggesting that it is a safe oral supplement for those with autoimmune disorders. Overall, ABBi16 shows promise in promoting a more regulated immune system.
9
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
8
S. cerevisiae aids autoimmune treatment
We evaluated the effects of Saccharomyces cerevisiae and its selenized form, Selemax, on experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
Mice receiving both supplements showed improved symptoms and a reduced immune response. Selemax was notably more effective, enhancing beneficial gut bacteria and promoting specific immune responses.
These findings highlight the potential for selenized S. cerevisiae to play a role in modulating the gut-brain connection, indicating its promise for future clinical trials.
References
- Tian C, Yan M, Guo J, Zhou Y, Du B, et al. Yeast Cell Wall-Mediated Ileal Targeted Delivery System for IgA Nepharopathy Therapy. ACS Biomater Sci Eng. 2025;11:1498. 10.1021/acsbiomaterials.4c01941
- Vuscan P, Röring RJ, Kischkel B, Tintoré M, Cuñé J, et al. Effect of Saccharomyces cerevisiae β-glucan on the T helper cytokine profile. Cytokine. 2025;187:156871. 10.1016/j.cyto.2025.156871
- Lee C, Verma R, Byun S, Jeun EJ, Kim GC, et al. Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities. Nat Commun. 2021;12:3611. 10.1038/s41467-021-23929-9
- de Campos Fraga-Silva TF, Mimura LAN, de Oliveira LRC, Dos Santos Toledo JH, Borim PA, et al. Selenization of S. cerevisiae increases its protective potential in experimental autoimmune encephalomyelitis by triggering an intestinal immunomodulatory loop. Sci Rep. 2020;10:22190. 10.1038/s41598-020-79102-7
- Alvarez P, Augustín JJ, Tamayo E, Iglesias M, Acinas O, et al. Therapeutic Effects of Anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Treatment in Psoriasis and Arthritis. Arthritis Rheumatol. 2020;72:1547. 10.1002/art.41272
- Aboud C, Zamaria N, Cannistrà C. Treatment of hidradenitis suppurativa: Surgery and yeast (Saccharomyces cerevisiae)-exclusion diet. Results after 6 years. Surgery. 2020;167:1012. 10.1016/j.surg.2019.12.015
